Pharmaceutical Preparation by Membrane Selective electrodes Method
Abstract
This study includes method for determination Hyoscine Butylbromide (HB) in its pure form and in the Pharmaceutical Preparation (Spasmosam) . Amembrane selective electrode was made ; its liquid membrane contains the standard material (HB) with Phospho Molybdic acid (PMA) as an active materials and using Tributyl phosphate (TBP), Acetophenone (ACP) as a plasticizers , The results show that the electrode was made HB-PMA with TBP as a plasticizer was better than use ACP as a plasticizer and the slope for the electrode was made with TBP as a plasticizer gave Nernest`s slope near by the theoretical value for charge monadic ion was equal to 59.15 mv/decade , the correlation coefficient was near to unity , the recovery value and relation standard deviation was better than use ACP as a plasticizer .
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