Effect of phospholipase extracted from Aspergillus flavus and Aspergillus candidus on body weight of male mice

Abstract

The present study investigated the effect of phospholipase extracted from Aspergillus flavus and Aspergillus candidus on body weight of male mice by two stages of daily intrapretoneal injection with crude phospholipase, phospholipase precipitation with ammonium sulfate, and phospholipase with dialysis. The first stage was 7 days, while the second stage was for 14 days. The results showed that the treatment of male mice with 0.05 ml/day/animal of phospholipase caused the reduction of body weight reached for a significant level (P>0.05) with continue of injection, too the results indicated the effect of phospholipase was more in the dialysis phospholipase compared with other forms. The results showed that the effect phospholipase extracted from Aspergillus flavus was more than the effect of phospholipase extracted from Aspergillus candidus.