Combination Therapy with Anti Trichomonas vaginalis Plant Extracts

Abstract

The aqueous crude extract of Trigonella foenum graecum was prepared and its inhibitory effect on Trichomonas vaginalis was tested with a concentration 10mg/ml at different time exposure (24, 48, 72 and 96) hours compared with zero time (control), the results showed that the aqueous extract of T.f. graecum completely inhibited the growth of T. vaginalis at 48 hours, this effect was highly significant when compared with standard antibiotic (Metronidazole) commonly used for the treatment of T. vaginalis infection. In order to decrease the concentration of the aqueous T.f. graecum extraction, two extracts were mixed together at the same concentration such as: (5mg/ml of T.f. graecum + 5mg/ml of Thymus vulgaris, 5mg/ml of T.f. graecum + 5mg/ml of Matricaria chamomilla and 5mg/ml of T.f. graecum + 5mg/ml of Cyperus rotundus) to test the effectiveness of the combination. It was found that the mixing of two extracts produced a best effect.