Spectroscopic Study for Determination of Amoxicillin Using Cobalt(II) as Complexing Metal


This study includes analytical methods for the determination of the drug amoxicillin trihydrate (Amox.) in some pharmaceutical preparations using Cobalt ion (Co(II)) as complexing metal. The best conditions for complexation were: the reaction time was 20 minutes, pH=1.5 and the best temperature of reaction was 70 ˚C. Benzyl alcohol was the best solvent for extraction the complex.