UV Spectrophotometric Method for the Analysis of Tinidazole after Exposure to Superficial X-Rays

Abstract

The aim of the present work is to assess UV-spectrophotometric method for the effect of superficial X-rays on the tinidazole compound in two forms, solid and aqueous solution . Both acceleration potentials of 120 kVp and 160 kVp exert a pronounced effect on aqueous solution of tinidazole at different concentrations represented by changes in optic density of tinidazole . The effect of superficial X-rays on the solid form of tinidazole is less than that observed with the aqueous preparation . It concluded from these that tinidazole is radiosensitive compound and several protection measurements should be used to prevent its hydrolysis .