Streptococcus. Pyogenes And Staphylococcus. Aureus Specific Mucosal And Systemic Immune Responses Of Patients With Arthritis

Abstract

Injured St. pyogenes and injured S.aureus were recovered from ten arthritis patients synovial fluids cultures by pretreatment with enriched media. The synovial fluid analysis indicated septic arthritis type. Mucosal and systemic and inflammatory cells were neutrophlis. Systemic and mucosal globulin was higher than those of normal subjects. Arthritis patients showed significant specific antibody titres and significant leucocyte inhibitory factors both at mucosal and systemic arms, but the systemic was of high antibody titres and more significant LIF, than mucosal. Thus. S. pyogencs and St. aureus stimulate humoral and cellular responses