THE ACTIVITY OF SOME NEW PREPARED ALDONITRONES AS ANTIBACTERIAL AND SEDATIVE COMPOUNDS

Abstract

Anew prepared aldonitrones by using heterocyclic compounds have achieved. The Biological activity of the prepared aldonitrones compounds against Gram negative and Gram positive Bacteria was carried out. Some of the prepared aldonitrones showed highly inhibitions activities. The effect of some prepared aldonitrones on the physiological properties in mice such as muscle tone, reflex and swimming time have been measured. The aldonitrone compounds showed effective sedative characters .The most important property of the prepared aldonitrones that it show negligible median lethal dose which makes them promising antibacterial and sedative compounds .