•Serum levels of copper, zinc, iron and magnesium in Iraqi`s patient with chronic hepatitis C

Abstract

objective: This study was conducted to determine the alterations in serum trace elements, including zinc (Zn), copper (Cu), iron (Fe), and magnesium (Mg) in patients with chronic hepatitis C and to compare the results with those of age and sex matched healthy individuals.Methods: The study was carried out in Medical Research Unit, College of Medicine, Al-Nahrain University from 2009-2010. One hundred and ten subjects, 60 patients with chronic hepatitis C and 50 healthy individuals were included in this study. The serum zinc, copper, iron and magnesium concentrations were measured by using atomic absorption spectrophotometery.Results: Serum zinc, copper, iron and magnesium concentrations were found to be 1.081±0.08, 1.143±0.025, 0.0819±0.0188 and 27.455±0.409 mg/L respectively in patients with chronic hepatitis C and 1.086±0.4680, 1.103±0.326, 0.0339±0.0066 and 16.80±0.56 mg/L in healthy individuals, respectively. Serum iron was exhibited to be elevated significantly (p<0.01) and magnesium was observed to be decreased significantly (p<0.01) in patients when compared with those of the control group. However zinc and copper remained without significant variants.