ALLERGENIC ACTIVITY OF FISH EXTRACT

Abstract

A component of Fish extract has been isolated by a combination of 65% ammonium’ sulphat salt precipitation and gel filtration. The purified allergen appeared as two majorpeaks. Peak 1 1 exhibited the highest lglj binding inhibition and showed a specific. allergenic activity about two fold higher than that of the peak 1. Peak 1 and peak 11 crossreacted in IgE binding inhibition. Completely inhibiting the binding of specific IgE to eachother. The allergencity of purified allergen was not lost during purification process.

Keywords

fish, Extract, Allergy