ALLEREGENIC ACTIVITY OF BOVINE DANDER EXTRACT

Abstract

This study was conducted in Basrah at period from March through July 2000.The protein extract from Bovine dander was prepared with extraction followed bypurification and fractionation by gel filtration into tow peaks. Elisa inhibition withserum samples from 77 patients who were sensitive to bovine dander, revealedsimilar lgE,lgG binding patterns for each peak. Also, there is a cross —reaction .between these two peaks.PeakII exhibited the highest IgE binding inhibition andshowed a specific allergenic activity about two fold higher than that of peakI.Theallergenecity ofpurified allergen was not lost during purification process.

Keywords

Elisa, Dander, IgE