SYNTHESIS AND PHOTO- IRRADIATION OF SOME PYRIMIDINE AND PURINE DERIVATIVES

Abstract

The current study included the synthesis of a series of azo compounds. These compounds were prepared by coupling nitrogen bases with phenyl diazonium salts. While the azo Schiff compounds were prepared by direct condensation of the prepared azoaldehydes with the nitrogen bases (2-amino pyrimidine & guanine ). The Schiff base derivatives were prepared by direct condensation of nitrogen bases (2-amino pyrimidine & adenine) with substituted benzaldehyde and chloral.The structures of the prepared compounds were confirmed by spectral analysis including ultra-violet visible and infra red spectra. Also photo irradiation of these compounds at (=356nm) has been done to study the stability of these compounds. The results revealed complete disappearance of the (OH) and (NH) bands in a number of compounds and partial disappearance in others which reflects the photo-oxidation or hydrogen bonding for the groups of (OH) or (NH).The disappearance of the (NH2) and (C=O) bands conforms the successful of prepared compounds.