Study of the Correlation between high sensitivity C reactive protein and Each of Malondialdehyde , Lipid profile, and Atherogenic Index inPatients with Ischemic Heart Diseases(IHD) in Thi-Qar Governorate


Objective: Ischemic heart disease (IHD) is estimated to be leading cause of mortality in the world and in high-income countries. The present study was designed to determine and compare the levels of (hsCRP, MDA, lipid profile, and atherogenic index)in patients with (IHD) and healthy individuals and asses the titer of hsCRP among different types of IHD to predict its role in the risk stratifications of Ischemic Heart Disease and healthy individuals. Material and Methods:Serum high sensitivity C reactive protein ,lipid profile ,malondialdehyde, and atherogenic index levels were measured in 100 patients Ischemic Heart Disease and 70 supposedhealthy subjects .Results:The levels of serum high sensitivity C reactive protein , malondialdehyde, biochemical markers of lipid profile (serum TCH,TG,LDL,VLDL)and atherogenic index (AI) were revealed significant increase in patients with coronary artery disease as compared to control group whereas the levels (HDL) showed a significant decrease in coronary heart disease patients in comparison to control subjects(P ≤ 0.01).This study was also revealed the correlation between the concentrations of the measured parameters and hsCRP.This study revealed significant in hsCRPin patients with (IHD). Conclusion:This study revealed significant inhsCRPin patients with (IHD).Lipid peroxidation and oxidative stress is more prominent in patients with (IHD) comparison to healthy individuals ,and this is mostly the leading cause of atherosclerotic processes and resultant complication of coronary occlusion . this lipid peroxidation reflected by (hsCRP, MDA, LDL, and atherogenic index ) were obvious in this study .