MMP-2 and TIMP-2 markers for immunohistochemical study on the prenatal development of the rat's primary visual cortex

Abstract

Abstract:The objective of this study is to relate the prenatal changes with thespatiotemporal pattern of expression and/or activity of the studied markers. Thechemical and molecular determinants of the development will be analyzed in atrial to understand some of the factors controlling these prenatal developmentalevents. Expression of many genes in various areas of the brain is age anddevelopment related and may undergo an irreversible change. Therefore, it isvery important to study the normal expression of various proteins in order todelineate their physiological functions.Eighteen embryos were used, six embryos for each embryonic age (E16,E18 and E20), three for studying MMP-2 immunohistochemical marker and