Effect of Sesame Oil on Kidney Function and some Biochemical parameters in adult male Rabbits

Abstract

This study was designed to find out the effect of (Sesame oil) on some biochemical parameter in blood plasma associated with kidney function in adult male rabbit by giving these animals sesame oil (1000mg/kg) B.W.which equal (1ml/kg) B.W. orally. Twenty adult male Rabbits were divided randomly into two equal groups: Control group (C) :each animal of this group given normal drinking water and diet, treatment Group (T) :each animal of this group given Sesame oil (1000mg/kg B.W.) orally for 6 weeks Blood samples were collected in 2, 4, 6 week of experimental period to measure (glucose, cholesterol, Triglyceride, urea and creatinin) in blood plasma. At the end of experiment three animals of both control group and treated group with sesame oil were sacrificed to examin the histological structure of the kidney, This study revealed that Sesame oil which was given orally caused significant decrease (P<0.05) in plasma (glucose, cholesterol and TG) while Sesame oil caused no significant decrease (P>0.05) in plasma urea and creatinin concentration,there was no histological changes in kidney tissue of the treated group in compared with control group. Results of this study have shown the potency of Sesame oil as indicated by its effect on animals and human health through lowering glucose, cholesterol,triglyceride,urea and creatinin level in plasma.