Seroepidemiological Study of Hepatitis B virus infection among Blood Donors and Risky Groups in Diyala

Abstract

Abstract: Subject: To explore the prevalence of hepatitis B virus infection among blood donors and risky groups in Diyala province and their relevance to epidemiologic factors.Materials & methods: In this study, the records of HBsAg screening and confirmatory tests of virology unite/public health laboratory/ Baquba were reviewed for the period 1989 to 2000. Different generations of enzyme-linked immunosorbant assays (ELISA) were used throughout this period. Demographic information including, age, sex, residence, occupation and time of diagnosis were also collected. All data were statistically analyzed.Results: The grand prevalence of HBV infection in blood donors was 1.5%. The prevalence rates in risky groups were as follows; hemophiliacs (42.8%), Acute icteric cases (13.6%), thalassemics (10.2%), household contacts (10.1%), hemodialysis patients (7.5%), prisoners (3.1%), health care workers (2.7%), barbers (1.9%) and midwives (0.5%). There was male to female predominance of 2.6:1, and the age group (16-29 years) was mostly affected (46.2%). The highest prevalence was found in 1991 (4.7%). Regarding the geographical distribution, Al-Mukdadia sector showed the highest prevalence (24.6/105 population), while the overall prevalence in Diyala was 17.9/105 population). The majority of HBsAg positive cases were diagnosed among blood donors.Conclusion: Diyala province rank in the intermediate zone of HBV endemicity. Seroepidemiologic surveillance provides a comprehensive picture of the HBV infection and the relevant factors that are important in evaluating the effectiveness of control measures.Key ward: Seroepidemiological, Hepatitis B, Blood Donors, Risky Groups, Diyala