Determination of IGE level in Asthmatic Adult Males Patients on Attack and Rest Period


Abstract Sixty male patients with asthma were included in this study, their age ranged between 18-24 years (mean 20 ±1.3). Forty-five were in attack state and fifteen were in rest (between the attacks). All cases were admitted to Al-Rasheed military hospital during November 2001 and April 2002.Twenty age matched apparently healthy en were included as a negative control. Eight males with signs and symptoms of asthma (mostly chronic bronchitis patients) were regarded as a positive control. Ten ml of blood sample were withdrawn from each patient as well as from controls.IgE level was measured by enzyme linked immunosorbant assay (ELISA) in which a significant elevation were noticed in both groups attack and rest groups in comparison with control groups.Key wards: IGE, Asthmatic, immune response.