Pathological Study of Campylobacter jejuni in adult mouse model


The Gram-negative, spiral, microaerophilic bacterium, Campylobacter jejuni, has established itself as the leading cause of food- and water-borne human gastroenteritis in both developed and developing countries, The spectrum of disease may range from mild, self-limiting, non-inflammatory diarrhea to severe, inflammatory, bloody diarrhea with fecal leukocytes, pyrexia, abdominal cramps and bacteraemia (33).and this gastroenteritis is sometimes followed by unprecedented complications, ranging from localized peritonitis, pericarditis, hepatitis and encephalopathy to generalised neuropathy and bacteraemia.