The Effect of Low to Medium Dose Inhaled Beclomethasone Dipropionate on Blood Glucose Level in patients with Bronchial Asthma

Abstract

ABSTRACT:BACKGROUND: Although inhaled corticosteroids (ICSs) are the mainstay of therapy in asthma, their use raises certain safety concerns.OBJECTIVE: This study aimed to evaluate the effect of inhaled Beclomethasone dipropionate on glucose level in patients with bronchial asthma .PATIENT AND METHOD: Ninety patient with new diagnosis of bronchial asthma were included in this study. Patients divided into two groups: 1st group includes those who are controlled with inhaled salbutamol only (30 patients). The 2nd group includes those who required also regular beclomethasone (60 patients). Fasting blood glucose and HbA1c was measured for all patients in both groups before and after three months of starting treatment. RESULTS:There was significant elevation of both FBS and HbA1c in group 2 patients after starting inhaled beclomethasone dipropionate in comparison to their baseline levels and the levels in group 1.CONCLUSION: The findings indicate that inhaled beclomethasone dipropionate in asthmatic patients may disturb blood glucose level