The effect of radiotherapy treatment on some blood elements in patient with some types of cancer

Abstract

Back ground: Cancer is a term used for diseases in which abnormal cells divide without control and are able to invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph system. Radiotherapy is one type of treatment used to treating patient with cancer, the most common form of irradiation is the use of external beam photons or electrons. Photons are X-ray or У-ray and may be considered as bundles of energy that deposit dose as they pass through matter. Objectives: 1-The effect of radiotherapy on the blood system and some blood parameters. 2.To record the White blood cells count, red blood cells count and hemoglobin level before and after radiotherapy. Materials and patients: The study carried out in Rizgari teaching hospital / Oncology department from Sample size determined by 50 patients distributed as follow: 10 patients for each: skin cancer, breast cancer, lung cancer, brain cancer, colon cancer. Blood obtained from each patients and complete blood picture (CBP) done for them before and after completing the total doses of the radiotherapy Results: The mean value of white blood cells decreased significantly (p value=0.000) after radiotherapy treatment in all types of cancer which included in the study. The mean value of red blood cells decreased significantly(p value<0.005) after radiotherapy in all types of cancer which included in the study and also the mean value of hemoglobin level decreased significantly (p value=0.000) after radiotherapy treatment in all types of cancer which included in the study. Conclusions: There were a negative effect of RT on the blood count which lead to decrease the mean count of WBCs , RBCs and Hb level which adversely lead to other side effects like infection, anemia, weight loss and bleeding.