The Effect of Heptachlor on Histology of Seminiferous Tubule and Mice Testis Activity


The study was aimed to illustrate the effect of heptachlor on seminiferous tubule and spermatic cells in the testis of mice .Heptachlor 10 mg / kg was given daily by gulping for five weeks. Mice were sacrificed after injected with colchicines in traperitonially , testis were collected after 7,21,36 days to study the effect of heptachlor on histo-testis and improved heptachlor activity not as chemical mutagen but as a tumor promoter by act directly on DNA which reflected on decreasing testicular Leydig cell and spermatogenic deficiencies when comparison with control and vitamin C.