Spindle Cell (Sarcomatoid) Carcinoma of the Larynx -- Case Report --


A 56 year old male patient presented with a history of recurrent attacks of progressive hoarseness and stridor for the last 9 months, he underwent six laryngeal surgery and the biopsy results were negative for malignancy except the last pathology report which revealed the diagnosis of spindle cell carcinoma of the larynx confirmed by immunohistochemistry. The patient refuses radiotherapy and went to India where they failed to diagnose the disease. The presented case demonstrates that spindle cell carcinoma or sarcomatoid carcinoma is very rare malignant tumor of the larynx but should be suspected in spindle cell tumours of the larynx and awareness of the pathologist to the unusual immunohistochemical presentation of this tumor with the use of expanded immunohistochemical markers panel.