The Comparison Study between Serum and Salivary Steroid Hormones in Young Ages

Abstract

Saliva is composed of a complex mixture of mucins, enzymes, antibodies, electrolytes, and hormones, all of which serve to begin the process of digestion and protect the oral mucosa. Saliva testing is proving to be the most reliable medium for measuring hormone levels. Hormone levels in saliva accurately represent the amount of hormone delivered to receptors in the body, unlike serum, which represents hormone levels that may or may not be delivered to receptors of the body. (30 male and 35 female) serum and saliva samples were collected for young student age (18-22) year. Samples were collected from November 2012 to February 2013 of Tikrit University students. All samples were normal individual who no personal or family history of any diseases. Serum and saliva (Testosterone, Progesterone, Estrogen and Cortisol) were determined by using AccuBind ELISA Microwells. All serum steroid hormones were increased when compared with saliva in male but in female serum steroid hormones were increased rather than saliva except serum testosterone which decreased. Measurements of salivary hormone levels are of clinical importance if they accurately reflect the serum hormone levels or if a constant correlation exists between salivary and serum hormone levels.