@Article{, title={Correlation between crevicular C-reactive protein level with its serum level in chronic periodontitis patients}, author={Basima Gh. Ali}, journal={Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد}, volume={26}, number={3}, pages={84-88}, year={2014}, abstract={Background: The main purpose of this study is to find if there is any correlation between the level of C-reactiveprotein (CRP) in gingival crevicular fluid with its serum level in chronic periodontitis patients and to explore thedifferences between them according to the probing depth.Materials and methods: Forty seven male subjects enrolled in this study. Thirty males with chronic periodontitisconsidered as study group whom further subdivided according to probing depth into subgroup 1 with pocket depth≤6mm, subgroup 2 with pocket depth >6mm. The other 17 subjects considered as controls. For all subjects, clinicalexamination where done for periodontal parameters plaque index (PLI), gingival index (GI), bleeding on probing(BOP), probing pocket depth (PPD) and clinical attachment level (CAL). The gingival crevicular fluid (GCF) werecollected using filter paper size 30 from gingival sulcus of the controls and from (138) pocket site (75 sites > 6mm. and63 ≤ 6mm.). The weight of the GCF was measured by reading the difference in the weight of filter paper before andafter absorption of GCF. Crevicular level of CRP was measured calorimetrically. The serum level CRP was measuredusing latex test.Results: Highly significant difference in the weight of GCF, crevicular and serum level of CRP between chronicperiodontitis and control groups. Subgroup 2 got higher scores of weight of GCF and positive record of crevicularand serum CRP compared with subgroup 1 with a non-significant difference. A highly significant difference in thenumber of sites with positive crevicular and serum CRP compared to the negative number between chronicperiodontitis and control groups also between subgroup1 and subgroup 2.Weight of GCF gets a negative significant correlation with GI at control group and subgroup2. Serum level of CRPexhibits a negative significant correlation with PLI for chronic periodontitis and control group and positive significantcorrelation for GI at subgroup 1. The crevicular CRP get significant negative correlation with GI of subgroup 1.Conclusions: Crevicular fluid is very good marker for the degree of inflammation of the periodontal pocket. Thecrevicular level of CRP may be considered as a good tool for estimating the systemic effect and predictor for theeffect of periodontitis on the general health and the correlation of crevicular with serum CRP aid to high light thiseffect.

الھدف الرئیسي من ھذه الدراسة ھو معرفة تركیز البروتین الارتكاسي في السائل اللثوي ومقارنتھ مع تركیزه في مصل دم مرضى النسغاغ المزمن بالمقارنة معالمجموعة الضابطة ایضا تحاول الدراسة ایجاد علاقات بین تلك التراكیز ومؤشرات ماحول الاسنان السریریة في مجموعة الدراسة والمجموعة الضابطة. توصلتالدراسة الى انھ ھناك فرق واضح في التراكیز بین كلا المجموعتین وكذلك فان مستوى البروتین الارتكاسي یختلف باختلاف شدة الاصابة بمرض النساغ المزمنوخلصت الدراسة الى ان مرضالنساغ المزمن مع مؤشراتھ المناعیة قد یعكس صورة تاثیر ھذا المرضعلى الصحة العامة} }