TY - JOUR ID - TI - Estimation of Serum Copper, Manganese, Selenium, and Zinc inHypothyroid Patients AU - Yildiz Hassan Tahs AU - Hussein Kadhem Abdul Hussein AU - Eham Amir Ali ) PY - 2008 VL - 50 IS - 2 SP - 255 EP - 260 JO - Journal of the Faculty of Medicine Baghdad مجلة كلية الطب SN - 00419419 24108057 AB - Summary:
Background: Decreased thyroid hormone synthesis and low levels of circulating
thyroid hormones result in clinical and biochemical changes in hypothyroidism. As
deficiency of thyroid hormones causes many metabolic processes to slow down,
therefore; the maintenance of optimal health requires an adequate supply of
carbohydrates, proteins and lipids, and macronutrients, micronutrients, and trace
elements.
Objective: Study the effect of the changing in serum level of the trace elements;
Zn, Cu, Mn, and Se in hypothyroid patient.
Patients and Method: Thirty seven hypothyroid patients and fifteen normal
healthy control persons were participated in this study.
Serum zinc and copper were determined using flame atomic absorption
spectrophotometer. While determination of manganese and selenium were done
using flameless atomic absorption spectrophotometer.
Results: Serum Zn and Se level were significantly decreased in hypothyroidism,
while there was significant increase in serum Mn level as compared with control
group. Furthermore there was no significant difference in serum Cu level between
groups.
Conclusion: the results of this study suggest that the metabolism of Zn, Mn, and Se
is abnormal in hypothyroid patients.

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