TY - JOUR ID - TI - Study the Relationship between Toxoplasmosis and Human Leukocyte Antigen Class I in Some Iraqi Aborted Women AU - Mohammed Abdul-Daim Saleh PY - 2015 VL - 26 IS - 2 SP - 18 EP - 23 JO - Al-Mustansiriyah Journal of Science مجلة علوم المستنصرية SN - 1814635X 25213520 AB - This study was aimed to investigate a possible relationship between the toxoplasmosis and human leukocyte antigen (HLA) class I in some Iraqi aborted women. Blood samples were collected from 40 Iraqi aborted women with age ranging from (18 – 39) years who gave positive results for anti-toxoplasma IgM antibody referred to AL-ulwea Hospital for delivery .In addition, a total of 40 apparently healthy women and negative for anti-toxoplasma IgM antibody with age ranging from (20 – 39) years were selected as a control group. The study was carried out during the period from 1/9/2012 to 15/9/2013. The results showed that highly significant frequencies of HLA-A29 , A31 and A34 antigens in patients group than control group with P value (0.001) .Besides , HLA-B8 and B35 Locus increase in patients group than control group with highly significant importance (P<0.001). Additionally , the results of HLA typing class I-C antigens has showed that the antigen frequency of HLA-Cw4 and Cw8 are highly significantly increased (P<0.001) in patients group as compared to control group . In conclusion : significant relationship was found between acute stage of toxoplasmosis in aborted women and certain HLA class I alleles (HLA-A29 , A31 , A34, B8 , B35, Cw4 and Cw8).

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