@Article{, title={Toxoplasmosis in the children who afflicted with congenital deformities and chronic diseases}, author={Baqir Kareem Abed باقر كريم عبد and Ahmed A. Al-Saadi احمد الساعدي and Tareef Fadhil Raham طريف فاضل رحم and Amal Jabar Ghaib آمال جبار غايب}, journal={Al-Qadisiyah Medical Journal مجلة القادسية الطبية}, volume={11}, number={19}, pages={211-218}, year={2015}, abstract={Background:-Toxoplasmosis is an infectious disease caused by Background:-Toxoplasmosis is an infectious disease caused by unicellular opportunistic parasite called Toxoplasma gondii. The disease can be very serious and even fatal in fetuses, newborns, and individuals with weakened immune systems, in addition to the risk of gestation complications and congenital problems. Aims of the study:- The purpose of the present study to determine the relationship between Toxoplasmosis in the children who afflicted with congenital deformities.Materials and Methods:- The eighty eight samples were collected (blood) from the children who afflicted with congenital deformities in Al Alwaiya Children's Hospital and used ELISA technique to determine IgM and IgG Toxoplasmosis, in addition to eighty eight apparently healthy children as a control group.Results:- The results showed that among eighty eight children afflicted with congenital deformities there are 21 (23.86%) positive for IgM and 33 (37.50%) positive for IgG, while the results of IgM and IgG in the control group were 3 (3.14%) and 7 (7.95%) respectively with highly significant variation p=0.001. Conclusion:- The present study showed there is a relationship between the infection by this parasite and congenital deformities. But it cannot be certain Toxoplasmosis is the real cause of congenital deformities in those children, and in the same time it doesn't deny the impact. unicellular opportunistic parasite called Toxoplasma gondii. The disease can be very serious and even fatal in fetuses, newborns, and individuals with weakened immune systems, in addition to the risk of gestation complications and congenital problems. Aims of the study:- The purpose of the present study to determine the relationship between Toxoplasmosis in the children who afflicted with congenital deformities.Materials and Methods:- The eighty eight samples were collected (blood) from the children who afflicted with congenital deformities in Al Alwaiya Children's Hospital and used ELISA technique to determine IgM and IgG Toxoplasmosis, in addition to eighty eight apparently healthy children as a control group.Results:- The results showed that among eighty eight children afflicted with congenital deformities there are 21 (23.86%) positive for IgM and 33 (37.50%) positive for IgG, while the results of IgM and IgG in the control group were 3 (3.14%) and 7 (7.95%) respectively with highly significant variation p=0.001. Conclusion:- The present study showed there is a relationship between the infection by this parasite and congenital deformities. But it cannot be certain Toxoplasmosis is the real cause of congenital deformities in those children, and in the same time it doesn't deny the impact.

داء المقوسات هو مرض يسببه طفيلي وحيد الخلية انتهازي يسمى مقوسة گونداي, المرض يمكن أن يكون خطير جدا وحتى مميت في الأجنة والمواليد الجدد، والاشخاص ذوي المناعة الضعيفة، بالإضافة إلى خطر حدوث مضاعفات الحمل والمشاكل الخلقية. هدفت الدراسة الحاليه لتحديد العلاقة بين داء المقوسات في الاطفال الذين يعانون من التشوهات الخلقية في مستشفى العلوية للأطفال في محافظة بغداد/ الرصافه للفترة من تشرين الاول لسنة 2012 الى نهاية كانون الثاني لسنة 2013 .جمعت العينات (الدم) من الاطفال في المستشفى المشار اليها واستخدمت تقنيه الامتزاز المناعي (ELISA (لتحديد الكلوبيولين المناعي IgM)) وIgG)) لثمانية وثماننين طفلا يعانون من مختلف التشوهات الخلقية تراوحت اعمارهم بين عمر يوم واحد الى خمس عشرة سنه بالأضافه الى ثمانية وثمانين طفلا اصحاء ظاهريا كمجموعة سيطرة. أظهرت النتائج ان من بين ثمانية وثمانين طفلا مصاب بالتشوهات الخلقية هنالك 21 (23.86%) نتيجة موجبه لكلوبيولين IgM و 33 (37.50%) نتيجة موجبة لكلوبيولين IgG بينما نسبتي IgG ,IgM في مجموعة السيطرة كانتا 3 (3.14%) و 7 (7.95%)على التوالي.} }