TY - JOUR ID - TI - The Effect of Zinc Oxide Nanoparticles on Streptococcus mutans of Human Saliva (In Vitro Study) AU - Suha T. Abd AU - Abbas F. Ali عباس فاضل PY - 2016 VL - 28 IS - 2 SP - 158 EP - 164 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: Nanotechnology represents a new science that promises to provide a broad range of uses andimproved technologies for biological and biomedical applications. One of the reasons behind the intense interest isthat nanotechnology permits synthesis of materials that have structure is less than 100 nanometers. The present workrevealed the effect of zinc oxide nanoparticles (ZnO NPs) on Streptococcus mutans of Human Saliva in comparisonto de-ionized water.Materials and methods: Streptococcus mutans were isolated from saliva of forty eight volunteers of both sexes theirage range between 18-22 years and then purified and diagnosed according to morphological characteristic andbiochemical tests. Different concentrations of ZnO NPs were prepared from the stock solution; all the experimentswere conducted in vitro. Disk diffusion method was used to study the sensitivity of Streptococcus mutans to differentconcentrations of zinc oxide nanoparticles in comparison to effect of de-ionized water.Results: Streptococcus mutans were sensitive to concentrations (0.05, 0.1, 0.5, 1, 3 and 5.8) mg / ml of the zinc oxidenanoparticles solution in comparison to de-ionized water, revealing a highly significant difference in allconcentrations except for concentration (0.01) mg / ml which was showed no significant difference in comparison tode-ionized water.Conclusion: This study revealed that zinc oxide nanoparticles were effective against Streptococcus mutans

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