@Article{, title={Measurement of salivary Immunoglobulin A of participants with a healthy, gingivitis and chronic periodontitis conditions}, author={Suzan Ali Salman سوزان علي سلمان}, journal={Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد}, volume={27}, number={3}, pages={120-123}, year={2015}, abstract={Background: Secretory Immunoglobulin A (SIgA) is a subclass of Immunoglobulin A (IgA), It is an antibody that playsan important role in mucosal immunity. It is the main immunoglobulin found in mucous secretions from mammaryglands, tear glands and salivary glands, every pathologic process in the body involves the immune system, andperiodontal inflammation is one of them and is not an exception.Material and methods: this study was consisted of 60 healthy male participants of an age ranged between (35-50)years old ; 25 of them with generalized moderate chronic periodontists(Clinical Attachment Loss equal to 3-4mm at ≥30% of the sites; 20 participants with plaque induced gingivitis and 15 participants had clinically healthyperiodontium as control group. oral examination include Plaque Index, Gingival Index, Probing Pocket Depth andClinical Attachment Level were conducted for all participants four sites were examined for each tooth (labial,lingual, mesial and distal), 2ml of unstimulated whole saliva was collected from all participants to measureSecretory Immunoglobulin A in μg /ml by Enzyme-linked immunosorbent assay technique.Results: salivary IgA(sIgA) mean was (356.3) μg /ml for the chronic periodontitis patients; while it was 202 μg /ml forplaque induced gingivitis patients and it was 129.2 μg /ml for the control group. Highly significant differencesamong the three group were recorded (P-value <0.001). For chronic periodontitis patients, the Plaque Index GingivalIndex scores were positively highly significant correlated with Secretory Immunoglobulin A level in saliva. The ProbingPocket Depth scores were positively and significantly associated with Secretory Immunoglobulin A level. The ClinicalAttachment Level scores were positively but non significant associated with Secretory Immunoglobulin A level. Forthe gingivitis and the control group they were positive non significant association between the periodontalparameters and the Secretory Immunoglobulin A level in saliva.Conclusion: there is a correlation between Secretory Immunoglobulin A level in saliva and the periodontal healthstatus.

} }