TY - JOUR ID - TI - Assessment of Magnesium and Calcium status in oral cancer patients AU - Marwan Al-Nimr AU - Suad AL-Ani AU - Seta A.Sarkis PY - 2009 VL - 21 IS - 1 SP - 66 EP - 69 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - ABSTRACT
Background: The aim was to determine whether Mg and Ca ions could serve as tumor markers.
Materials and methods: A total sample of 53 individuals was studied that includes 33 patients with oral cancer and 20
well-matching control. Estimation of Mg and Ca levels in the lymphocytes of healthy individuals and patients, in the
normal and diseased tissues of patients were performed using atomic absorption spectrophotometer.
Results: The values of both elements in the lymphocytes of patients were exchangeable according to the
histopathological diagnosis. They were generally elevated in comparison to the control. (Ca = (3.983±3.214mean
±SD), Mg = (2.598±2.364 mean ±SD). Decrease levels of either elements in the diseased tissues observed in
comparison to normal tissues in both sexes but it was more obvious in females than males (P<0.001 for Ca, P<0.002 for
Mg).
Conclusion: Patients with oral cancer are immune suppressed and immune disturbance could be the cause of the
results found in this work.
Key words: Magnesium, Calcium, lymphocytes, tissues, oral cancer. (J Bagh Coll Dentistry 2009; 21(1): 66-69)

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