TY - JOUR
ID -
TI - Comparison of amelogenin sub-proteins osteoinductive activity (Histopathological study)
AU - Riyadh O. Alkaisi
PY - 2008
VL - 20
IS - 1
SP - 24
EP - 27
JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد
SN - 18171869 23115270
AB -
ABSTRACT
Background: Enamel matrix proteins (EMP) represent one of the most effective members of the bone morphogenic protein (BMP) family.
Materials and methods: Chemical isolation of AM followed by isolation of AM sub-proteins was done using gel filtration chromatography and polyacrylamide gel. Beside that the histopathological pictures after the application of each AM sub-proteins in a bony defect created in the mandible of hamsters were observed.
Results: Only the intermediate molecular weight sub-protein (application showed a rapid healing process and new bone formation.
Conclusions: Among the 3 AM sub-protein only the intermediate one represents the bone morphogenic factor.
Key words: Enamel matrix proteins, AM sub-proteins. (J Bagh Coll Dentistry 2008; 20(1)24-27)
ER -