TY - JOUR ID - TI - 20- STUDY THE EFFECT OF BAY LEAF EXTRACTON THE SOMEBIOCHEMICAL PARAMETERS IN DIABETIC MALE RAT INDUCED BY ALLOXAN AU - Jian Ibraheem k., Adel M. Hassen Alzobidy PY - 2018 VL - 17 IS - 1 SP - 234 EP - 245 JO - Basrah Journal of Veterinary Research مجلة البصرة للابحاث البيطرية SN - 18138497 24108456 AB - The present study aimed to determine the ameliorative effect of bay leafextract(BLE) on some biochemical parameters of laboratory diabetic male rats(Rattusnorvegicas) induced by Alloxan .The study consisted of thirty adult male ratsrandomly divided into five equal group(six of each ). As follow :Group one theanimals treated by intra peritoneal injection (IP) of normal saline solution(0.25ml),Group two the animal treated by oral gavage with (BLE) at dose (500 mg/Kg/BW) daily .Group three , rats were treated I.P with 100 mg /Kg BW single doseof alloxan(Allox).Group four .The diabetic rats were given orally by oral gavagelow dose of ( BLE)(250 mg /Kg/BW ) daily. Group five ,diabetic rats were givenby oral gavage high dose of BLE(500 mg /Kg/BW ) daily for 3 weeks.At the endof experiments period ,rats were sacrificed ,blood were collected by cardiac punctureto investigate biochemical parameters which included glucose ,liver enzyme(ALT,AST and ALP ) lipid profile TG , TC ,HDL-c , LDL-c , ,Total serum protein,Blood urea, and Creatinine concentration . Result indicated a significant increasedin Glucose,ALT, AST, ALP, TC, TG, LDL-c ,urea, and Creatinineinin diabetic animalwhereas HDL-c significantly decreased

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