TY - JOUR ID - TI - Detection of insulin resistance in overweight and obese individuals الكشف عن مقاومة الأنسولين لدى الأشخاص الذين يعانون من زيادة الوزن والسمنة AU - Fargeen Ezzaddin AU - Leweza B. Abbass PY - 2011 VL - 15 IS - 1 SP - 74 EP - 79 JO - Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية SN - 19955588 19955596 AB - Background and objectives: This study was designed mainly to determine fasting serum insulin level and other parameters related to obesity, since Type II diabetes mellitus is the most prevalent problem associated with obesity. In Kurdish region, no previous studies about insulin essay in overweight and obese individuals have been executed. Measuring insulin level in overweight and obese individuals can give information about the body's sensitivity to insulin.Methods: Fasting blood samples were derived from (60) overweight individuals (30 males + 30 females) and from (30) normal weight individuals and were analyzed for insulin level by using an immuno assay method (ELISA method) whereas fasting blood glucose, Triglyceride(TG), Total Cholesterol(TC). High Density Lipoprotein(HDL), were estimated spectrophotometrically.Results: From total (60) overweight individuals 76.6% have insulin resistance. From this percent about 52% of those individuals were with family history of diabetes and 24% were with family history of obesity.Conclusion: Three relatively simple metabolic markers can identify overweight and obese individuals who are sufficiently insulin resistant to be at increased risk for various adverse outcomes are (TG level, ratio of TG to HDL, and insulin level).

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