TY - JOUR ID - TI - A Study of Adiponectin/Leptin Ratio in Adult Males with Metabolic Syndrome AU - Ann Khazaal Yaseen*, Yousra Ahmed Abdulateef PY - 2018 VL - 17 IS - 4 SP - 355 EP - 359 JO - Iraqi Postgraduate Medical Journal المجلة العراقية للاختصاصات الطبية SN - 83601608 98932708 AB - BACKGROUND:Metabolic syndrome is a disorder of energy utilization and storage. It is a multi-component diseasebrought on by a combination of life style and environmental factors, with some populationsexhibiting a genetic predisposition and type 2 diabetes. It is marked by abdominal obesity, elevatedlevels of triglyceride, low levels of HDL (good) cholesterol, high blood pressure and high bloodsugar levels. Metabolic syndrome is a significant risk factor for the development of both type 2diabetes and heart disease, also associated with fatty liver, and polycystic ovary syndrome.Recently two adipocytokines secreted from visceral adipose tissue leptin and adiponectin, havebeen recognized as key regulators of various metabolic disorder.OBJECTIVE:The objective of this study was to use the adiponectin to leptin ratio as a parameter and a lab indexto predict metabolic syndrome across adult males.METHOD:A total of 82 adult males with mean age of (38.47 + 9.27) were included in the study. Fifty eight(58) adult males were the metabolic syndrome group depending on the presence of any 3 out of 5of the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATPIII) criteriawhich include the following: (central obesity ≥ 102cm, triglyceride ≥150 mg/dl, HDL-Cholesterol˂40 mg/dl, blood pressure ≥ 130/85 mmHg and fasting serum glucose ≥100 mg/dl) as compared totwenty four (24) healthy adult males as the control group.RESULT:The findings showed that adiponectin/ Leptin ratio is significantly lower in metabolic syndromeadult males as compared to healthy adult males.CONCLUSION:In conclusion data indicate that adiponectin/leptin ratio is a plausible index for detecting thepresence of metabolic syndrome in adult males.

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