TY - JOUR ID - TI - The Role of Parental Chromosomal Abnormalities in Recurrent Miscarriage AU - Ali Faleh Al-Assadi AU - Saad Abdul-Bagi AU - Iyen Abdul-Hussain Abdullah PY - 2017 VL - 22 IS - 1 SP - 76 EP - 85 JO - The Medical Journal of Tikrit University المجلة الطبية لجامعة تكريت SN - 18131638 AB - Background: recurrent miscarriage is a difficult medical problem happening in about 103% of pregnancies. A proportion of cases with repeated miscarriages are caused by chromosomal abnormality in one of the parents. Most spontaneous miscarriages which happen in the first and second trimester are caused by chromosomal abnormalities. Several studies have been made to determine the role of chromosomal abnormalities in couple with repeated foetal loss in various countries, but related studies are very limited in our area.Materials and Methods: cytogenetic study was carried out for (81) couples, and samples were collected from peripheral blood. 2nd blood was incubated in complete lymphocyte culture media.Results: among the (81) couples, only (6) were found to have abnormal chromosomes. Both male and female in couple number (6) were affected (7.4%). The nature of those abnormalities is discussed.Conclusion: this study should be helpful in the region to understand the contribution of chromosomal abnormalities to the cases of repeated pregnancy loss.

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