@Article{, title={Evaluation of Osteocalcin and Reproductive Hormones in Men with Type 2 Diabetes in Misan Province/Iraq}, author={Eman Ali Al-Saidy, Zainab Abdul Jabbar Al-Ali}, journal={Medical Journal of Babylon مجلة بابل الطبية}, volume={17}, number={2}, pages={126-132}, year={2020}, abstract={Background: Diabetes mellitus (DM) is a group of metabolic disorders in which there are high levels of blood sugar over a prolongedperiod. DM can be accompanied by numerous complications, including different organ systems for instance skeleton and reproductivesystem. Objectives: The aim of the present study was to determine the levels of osteocalcin (OC) and reproductive hormones in men withtype 2 DM (T2DM) of Misan province from December 2018 to May 2019. Materials and Methods: The study population consists of110 men aged 35–49 years of whom 66 type 2 diabetic and 44 healthy men; patients with T2DM were divided based on the age into threegroups: the first (35–39) years, second (40–44) years, and third (45–49) years; patients with T2DM were also divided based on the body massindex into four groups: normal weight (18.5–24.9), overweight (25–29.9), obesity class I (30–34.9), and obesity class II (35–39.9) groups.Results: According to the age, the mean values of fasting blood glucose and glycosylated hemoglobin A1c (HbA1c) were significantlyhigher in diabetic subjects when compared with the control. OC increases significantly in the second and third groups as compared to control.Luteinizing hormone (LH) of the patients in the third group significantly increases as compared to the first group. Patients of the third groupincrease significantly compared to the patients in the first group. Follicle-stimulating hormone (FSH) means value no different significantlyaccording to the age. The testosterone (TT) mean value in compare between patients group, the third increase significantly in compare with firstgroup. Estradiol (E2) in the first group increases significantly as compared to control. Prolactin (PRL) in the first group decreases significantlycompared to control. According to the BMI, the mean value of fasting blood glucose and HbA1c was significantly higher in diabetic subjectswhen compared to control. OC value of T2DM significantly increases in the group obesity class II and overweight. LH, TT, and FSH werenot significantly significant compared with control. E2 value significant different in compare with control of obesity class I and class II. PRLdecreased significantly as compared to control in normal weight group; in patients of obesity class I, the E2 value increases significantly ascompared to patients of normal weight. Conclusions: This study revealed no relationship between OC and reproductive hormones and norelationship between OC and T2DM.

} }