TY - JOUR ID - TI - Plasma marker based hepatoprotective evaluation of some novelsynthesized benzofluorenone analogues: A medicinal chemistryapproach AU - Trimurti L. Lambata,*, Sujata S. Deob, Ashwin B. Butlec PY - 2017 VL - 3 IS - 1 SP - 39 EP - 45 JO - Karbala International Journal of Modern Science مجلة كربلاء العالمية للعلوم الحديثة SN - 2405609X 24056103 AB - In an extensive search program towards development of new hepatoprotective agents, a series of novel benzofluorenones havebeen synthesized. These newly synthesized benzofluorenone derivatives exhibited protection against carbon tetrachloride (CCl4)-induced hepatotoxicity. This activity was estimated by levels of biochemical parameters such as aspartate aminotransferase (AST),serum alanine transferase (ALT), serum alkaline phosphatase (SALP) and total proteins (TP) carried out by using regular assaykits.

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