TY - JOUR ID - TI - Correlation between High Sensitivity C‑Reactive Protein and Incident Type 2 Diabetes among Newly Diagnosed Renal Impairment Patients AU - Noor Thair Tahir AU - Hind Shakir Ahmed AU - Omar Khairi Mahmmod PY - 2020 VL - 33 IS - 1 SP - 10 EP - 14 JO - IRAQI JOURNAL OF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع SN - 16845382 AB - Background: Numerous markers of inflammation like C‑reactive protein (CRP) are raised considerably in the diabetic population. The levels of these markers also associate with the severity of diabetes and presence of various complications. Objective: The objective was to study the correlation between CRP and glycemic control in type 2 diabetic patients who were newly diagnosed renal impairment and to evaluate if good glycemic control reduces the CRP values. Patients and Methods: This work was performed from June 2018 to January 2019. Forty‑five type 2 diabetic patients who were newly diagnosed renal impairment are included after proper screening, between 48 and 60 years of age at the National Diabetic Center/Al‑Mustansiriyah University. They were equated with 45 healthy subjects as control group. Then, relevant tests were done which are involved: fasting serum glucose, glycated hemoglobin (HbA1c), urea, creatinine, serum lipid profile, and serum high sensitivity CRP (hs‑CRP). Results: A significant increase in serum urea and creatinine was found in diabetic patients as paralleled to the controls. Furthermore, there was a significant difference in hs‑CRP in diabetics as compared to the controls (13.95 ± 5.42 mg/l vs. 2.0 ± 1.16 mg/l, P = 0.01, odds ratio = 1.157). Well glycemic control is foremost to the decline in HbA1c moreover caused a reduction in CRP levels when HbA1c was ≤7. Conclusions: It has been concluded that higher levels of CRP can be a prognostic element for the progress of type 2 diabetes, Also, it has a positive correlation with HbA1c, reflecting the glycemic status of the patient. Keywords: C‑reactive protein, diabetes mellitus, glycated hemoglobin, renal impairmene

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