TY - JOUR ID - TI - The Association Between Adiponectin with Lipid Profile and Troponin in Acute Myocardial Infarction Patients AU - Ammal Esmaeel Ibrahim PY - 2012 VL - 11 IS - 1 SP - 50 EP - 56 JO - Iraqi Postgraduate Medical Journal المجلة العراقية للاختصاصات الطبية SN - 83601608 98932708 AB - ABSTRACT:BACKGROUND:Adiponectin is thought to be exclusively synthesized by adipocytes; however, a recent suggestionstated that adiponectin is also synthesized and secreted by human cardiomyocytes. Adipose tissueis increasingly recognized as a key regulator of energy balance, playing an active role in lipidstorage and buffering, and synthesizing and secreting a wide range of endocrine products that maybe directly involved in the pathogenesis of the complications associated with obesity. So obesityconsider the major independent risk factor for atherosclerotic cardiovascular disease AcuteMyocardial Infarction (AMI), is the interruption of blood supply to part of the heart, causing someheart cells to die. Insulin is a very important hormone as it regulates the level of glucose, in theblood. Troponin is a complex of three regulatory proteins that is integral to muscle contraction inskeletal and cardiac muscle.OBJECTIVE:To monitor adiponectin level and its effect on lipid profile and Troponin levels in AcuteMyocardial infarction patients.SUBJECTS AND METHODS:The study included 50 patients with Acute Myocardial infarction and forty healthy subject ascontrol group. This study designed to measure adiponectin, lipid profile and troponin levels.RESULTS:Levels of adiponectin, cholesterol, LDL-C and Troponin were significantly elevated with(p<0.001), while HDL-C was significantly lower with (p<0.001), There was negative correlationbetween adiponectin with , cholesterol LDL-C, triglyceride and VLDL, and there was positivecorrelation between adiponectin with HDL in acute myocardial infarction.CONCLUSION:The significant increase in adiponectin in AMI may be related to inflammation. From the relationof adiponectin with lipid profile, adiponectin can increase level of HDL and decrease level oftriglyceride so this suggested that adiponection have anti-atherosclerosis properties

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