TY - JOUR ID - TI - CHLAMYDIA TRACHOMATIS AND RECURRENT SPONTANEOUS ABORTION IN IRAQI PREGNANT WOMEN AU - Farouk K Hasan فاروق خالد حسن AU - Amal H Salman أمال حسين سلمان AU - Nidhal AM Mohammed نضال عبد المهيمن محمد PY - 2012 VL - 10 IS - 1 SP - 42 EP - 46 JO - IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية SN - 16816579 22244719 AB - BackgroundCertain infectious agents have been identified more frequently in cultures from women who have had a spontaneous pregnancy loss; these include Ureaplasma urealyticum, Mycoplasma hominis, and Chlamydia.ObjectiveThe aim of the study was to evaluate the frequency of Chlamydia trachomatis infection among women who experienced recurrent spontaneous abortion.MethodsA total of 119 women, age ranged from 23.9−28.5 years were enrolled in the current study and were classified into: Group A- Recurrent spontaneous abortion (RSA): n= 62 women, with a mean age of (28.5±0.68); Group B- non- recurrent spontaneous abortion (non-RSA): n= 34 women, with a mean age of (26.4±0.85) and group C- Control (successful pregnancy): n= 23 women, with a mean age of (23.9±0.88). From each patient and control blood and urine samples were collected. Urinalysis test strips including Leukocytes esterase in urine was done, and estimation of IgM levels against Chlamydia trachomatis in sera of patients was done using ELISA method.ResultsBased on ELISA screening assay, results showed a significant difference in the level of circulating C.trachomatis specific IgM antibody between group A and group C (p< 0.05) as well as between group B and group C (p< 0.01). Also highly significant positive correlation (r=0.401, p<0.001) between C.trachomatis acute infection and urine level of leukocyte esterase.ConclusionC.trachomatis infection is an important causative agent of miscarriages in women. C.trachomatis infection diagnostic procedures should be considered in screening tests during pregnancy.Key wordsChlamydia trachomatis, RSA, ELISA, Leukocytes esterase

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