TY - JOUR ID - TI - SUB THALAMIC NUCLEUS DEEP BRAIN STIMULATION: IRAQI CASE SERIES AU - Mohamed AS Kamel محمد عبد الستار كامل AU - Ahmad AS Al-Atraqchy احمد عبد السلام الاطرقجي AU - Aqeel K Aljabiry عقيل كريم الجابري AU - Moneer K Faraj منير خماس فرج AU - Zaki N Hasan زكي نوح حسن PY - 2012 VL - 10 IS - 2 SP - 154 EP - 159 JO - IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية SN - 16816579 22244719 AB - Background: Sub thalamic nucleus (STN) Deep brain stimulation (DBS) electrodes are implanted into STN and programmed by external pulse generator. DBS alleviates the cardinal Parkinson disease symptoms and reduce the need for levodopa and related drugs and eventually reduces levodopa-related motor complications in advanced Parkinson's disease.Objective: To evaluate the STN DBS implantation in Parkinson disease patients.Methods: A retrospective evaluation of data base of the patients operated on for STN DBS between Jan. 2010 and Jan. 2011. The study involved 11 patients (10 males and 1 female) with an age range between 39 and 65. Surgical implantation was done in the Neurosciences Hospital in Baghdad. Unified Parkinson's disease Rating Scale was reported before surgery and 3 monthly after implantation. Paired t test was used to test the significance of difference between 2 means.Results: Highly significant differences (P < 0.0001) in the activities of daily living, Tremor, Rigidity, Bradykinesia and Gait parameter. There was no difference in Postural stability before and after. There was 65% of the patients reduced their levodopa medication dosage after STN DBS. One patient out of 11 (9%) developed intracerebral hemorrhage. Conclusions: STN DBS is very successful in managing motor clinical manifestations in advanced Parkinson disease and reducing levodopa medication. Key worlds: Parkinson, Deep brain stimulation, subthalamic

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