TY - JOUR ID - TI - Evaluation of the Serum and Tissue Levels of Copper and Zinc in Patients with Gynecologic Tumors.................. AU - Dr. Elham A. Mahdi AU - Layla A. Mohamad PY - 2009 VL - 2 no.6, 7 IS - 4 SP - 497 EP - 502 JO - Karbala Journal of Medicine مجلة كربلاء الطبية SN - 19905483 29580889 AB - serum and tissue copper (Cu) and zinc (Zn) levels were determined by atomic absorptionspectrophotometry in 20 women with malignant gynecologic tumors and compared withlevels in 15 with benign gynecologic tumors .A significant (p<0.05) elevation of serumcopper levels in gynecological cancer patients when compared with those of benigndiseases .Estimation of zinc level demonstrated a non statistically significant differencebetween malignant and benign gynecologic tumor patients . Determination of tissue copper andzinc contents revealed a significant (p<0.005) elevations of copper and non significant (p>0.005)decrease of zinc in malignant tissues with respect to those of benign tumors .In addition to it,there were essentially correlation between copper and zinc levels in serum and their levels intissue in cancer patients but no such correlation in patients with benign tumors.

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