@Article{, title={Treatment Failure of Tuberculosis in Diabetic Patients}, author={Mosa Ismail Al-Karawi; and Sadiq Al-Muhana;}, journal={Karbala Journal of Medicine مجلة كربلاء الطبية}, volume={2 no.8, 9}, number={5}, pages={630-634}, year={2009}, abstract={background: despite the availability of effective treatment , tuberculosis continues toinfect a large number of patients . Treatment failure is one of the major problems in theTB control programs.Objective: To evaluate the treatment failure in tuberculosis patients with diabetesmellitus.Patient & Method: In this retrospective study that extended from August 2007 toAugust 2008, 69 patients with tuberculosis and diabetes mellitus and 105 patientswith T.B. only, were included .All patients were from Al-Najaf and treated by ( DirectObserve Therapy programs)D.O.T.s .The patients are evaluated by the following data:- demographic data, site of disease by CXR, date of initial diagnosis of TB., purifiedprotein derivative (tuberculin test ) results , smoking history. The data were analyzedby using the statistical package social system (SPSS) and P. value <0.05 was regardedas statistically significant.Results: Patients with tuberculosis and diabetes mellitus were 69 (58 male and 11female) equal to(40%) of the total patients were treated with direct observe therapy(D.O.T.s) program, the treatment failure were 18 patients (12 male and 6 female)equal to (26%) of patients in this group. Patients with tuberculosis only were 105 (89male and 16 female) and equal to (60%) of the total patients were also treated with(D.O.T.s ),and the treatment failure were 10 patients ( 7 male and 3 female) that equalto (1o%) of patients in this group. The age group(30-50) years had a higher failurerate in both groups . The failure was more in males, smokers, with tuberculin testnegative, and in upper lobe lesions.Conclusion: There was a significant association between diabetes and failure in TB.treatment, which is more in male, smoker , in those have negative tuberculin test , andin TB of upper lobe of the lung .

} }