TY - JOUR ID - TI - Effect of Glycyrrhiza glabra extract on in vitro sperm activation and embiyonic development following intra-peritoneal insemination in mice: experimental model for mammals تاثير مستخلص عرق السوس على تنشيط النطف والتطور الجنيني بعد التلقيح عبر الغشاء البريتوني في الفئران:موديل تجريبي للبائن AU - saad s.aldujaily سعد صالح الدجيلي AU - zena muzher زينة مزهر PY - 2011 VL - 1 IS - 2 SP - 31 EP - 38 JO - Iraqi Journal of Embryos and Infertility Researches المجلة العراقية لبحوث الأجنة والعقم SN - 26166984 22180265 AB - Glycyrrhizaglabm(Gg) is a herbal medicine used in the treatment of different syndromes. Recently, the effect of this plant on the reproductive system has been studied. However, its role in in vitro still not dear.objectiveThe present study aims to investigate the possibility of using Glycyrrhiza glabra extract for in vitro sperm direct activation, and its effect on in vivo fertilization rate (FR) and early embryonic development (ED) following intra-peritoneal insemination (IPI ).The mice were used as an experimental model for mammals.Materials and methods:Glycyrrhiza glabra extract (2 mg/rnl culture medium) was used fix in vitro direct sperm activation technique. The female mice were divided into two groups: spontaneous^ ovulated (SQM) and superovulated groups (SuOM).Each group was divided into two subgroups, the first: the IPI was accomplished by epididymal sperm activated in vitro by adding 20%Gg to ihe culture medium .The second subgroup: the fP! is accomplished without adding Gg to Ihe culture medium.Revuein vitro activation of epididymal sperms with 20% Gg has shown positive effects on sperm concentration, sperm motility, and grade activity of progressive forward movement. There was a significant (P ER -