TY - JOUR ID - TI - Rhinocerebral Mucormycosis AU - Karim Q.AL.Naffi PY - 2006 VL - 1 no. 1 IS - SP - 8 EP - 16 JO - Karbala Journal of Medicine مجلة كربلاء الطبية SN - 19905483 29580889 AB - Rhinocereberal mucormycosis is a relatively rare opportunistic fungal infection, usuallyaffect patient with DM, renal failure, organ transplant, desferal user&rarely in healthyperson5, 7, 8,9,18. We try to look how frequent this disease is prevalent in the cases admittedto our hospital & what is the outcome of our treatment.MethodA prospective study done in Al-Hussein General Hospital-Karbala/Iraq in the period June2001-Augest 2005, to examine all patients with DM, CRF who have unexplained headache,facial edema, ophthalamoplgia or disturbed conscious for rhinocerebralmucormycosis.Diagnosis based on clinical suspicion , The presence of necrotic tissues innasal cavity, radiological exam including CT- scan whenever available &fungal detectionon of nasal swab &scraping..ResultWe diagnosed ten patients. Eight treated surgically &with amphotricin B (0.5mg/kg/d for sixweeks). Two were treated with amphotricin B&local cleaning only. Seven of those treatedpatients were cured; three died, those who died were presented late with ophthalamoplegiawith or without disturbed conscious.ConclusionRhinocereberal mucormycosis which is relatively rare disease actually is present in ourpatients especially those who have DM with or without renal failure or patient with CRF ondialysis3.13.16. It is a killing disease yet if we carry high index of suspicion in those caseswho is presented with headache, dirty nasal discharge, fever &facial edema. We can diagnosethem earlier &start treatment to control of the underlying condition, with aggressive surgicalinterventions combined with amphotricin B, we may safe many patients life.

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