@Article{, title={Effect of chemotherapy on oral health status and salivary alkaline phosphatase among leukemic patients}, author={Nadia A. Al-Rawi نادية الراوي and Raya R. Al-Dafaai ريا الدفاعي and Mohamad Sammi محمد سامي}, journal={Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد}, volume={25}, number={special issue 1}, pages={137-139}, year={2013}, abstract={Background: Leukemia is a broad term given to a group of malignant diseases characterized by diffusereplacement of bone marrow with proliferating leukocyte precursors. Chemotherapy has been increasingly used totreat malignant conditions. The systemic sequelae as a result of these immunosuppressive techniques induce manyoral and dental complications. This study was conducted to evaluate the effect of chemotherapy on oral healthstatus and activity of salivary alkaline phosphates enzyme in patients with acute lymphocytic leukemia.Materials and methods: The study groups included 28 patients with acute lymphocytic leukemia; they were underchemotherapy, aged 20-25 year old. The control group includes healthy subjects matching with study group. Plaque,gingival, calculus and loss of attachment status were recorded. After oral examination, stimulated saliva sampleswere collected from the subjects (study & control groups) and performed under standard condition followinginstruction and chemically analyzed for the detection of salivary alkaline phosphates enzyme.Results The study showed higher mean values of plaque index, gingival index, attachment loss and concentration ofsalivary alkaline phosphates enzyme among leukemic group than control group with statistically high significantdifferences.Conclusions: It was concluded that patients with acute lymphocytic leukemia have poor oral hygiene and needintense oral hygiene program before, during and after chemotherapy

} }