TY - JOUR ID - TI - Evaluation of Propolis from Kurdistan region as a new resinous sealer in root canal obturation-part I biocompatibility study AU - Dara Hama AU - Hussain Al-Huwaizi حسين فيصل الحويزي AU - Salim El-Samarri سالم السامرائي PY - 2013 VL - 25 IS - 3 SP - 8 EP - 13 JO - Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد SN - 18171869 23115270 AB - Background: Many materials were proposed as root canal obturating materials but the biocompatibility issueremains to be a critical one. Propolis has been used as a therapeutic agent since the time of Hippocrates. It is knownthat propolis exhibits some pharmacological activities, such as antibacterial, antiviral, antifungal and antiinflammatory activity.Materials and methods: Eighteen albino rats were used in the study and divided randomly into three groups of 6animals for each group. Each group was scheduled to be sacrificed at different time periods, which were threedays, one week and three weeks. Propolis and ZOE sealer implants of 4mm in diameter and 0.5 gm in weight wereimplanted in the dorsal side of the rats. At the end of the implantation, the rats were scarified and thehistopathological picture was made to the implantation site.Results: Zinc oxide eugenol sealer showed severe inflammation after 3 days of implantation whci subsided after 7days. After 21 days, moderate inflammatory reaction was evident. Propolis presented moderate reaction after 3 and7 days but with presence of signs of collagen fiber formation. After 21 days, connective tissue capsule was present.Conclusion: Propolis presented better biocompatibility than zinc oxide eugenol sealer

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