Abstract

This study was conducted in diyala governorate, with echocardiographic analysis of 12000 subjects to determine the clinical and epidemiological aspects of HCM from 1999-2005. Six thousands person were healthy and Six thousands patients who presented with cardiac complaints. Age range of the sample was 15-70 year, patients with known cardiac diseases or taking cardiac drugs were excluded. Thorough clinical history, physical examination, electrocardiography (ECG), chest radiographs, echocardiography (M-mode, two dimensional B-mode and continues wave (CW) Doppler mode) and standardized laboratory tests were performed .Our study showed that among 12000 persons screened 18 cases of proved HCM were diagnosed (0.15%),10 males(0.0833%) and 8 females(0.0666%),six cases 33.3% (3 males(50%) and 3 females (50%) were asymptomatic at diagnosis. Among six thousands patients presented with cardiovascular complaints (chest pain, dyspnea, palpitation, features of heart failure, pre-syncope and syncope) twelve (12) cases (0.01%) were diagnosed, seven males (58.3%) and five females (41.6%). Most of cases were in young age group: Fourteen patients (77.7%) were (20-39) years of age, and only 1<20 and 3 >40, male/female ratio was 1.25:1. Fourteen patients 77.7% were in NYHA -1 functional class and 5 patients (27.7%) had positive results on family screening for HCM. Echocardiographic study showed that fifteen patients (83.3) had asymmetrical septal hypertrophy (ASH) and 3 patients (16.6%) had concentric LVH. Doppler echocardiography showed substantial obstruction to left ventricular outflow tract (LVOT) in 7 (38.8%) patients (the range of the mean peak systolic pressure gradient was from 30 to 71 mm Hg: Hypertrophic obstructive cardiomyopathy. Thirteen subjects (72.2%) had abnormal ECG,atrial fibrillation reported in one patient (5.5%) .The estimated total prevalence of HCM in diyala governorate is 0.15% (150/100000).

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