Estimation of Specific Immunoglobulins E,A Antibodies and E-rosette in Allergic Patients.

Abstract

Background: Allergy is a hypersensitivity reaction mediated by immunological mechanisms which can be antibody or cell-mediated.Objective: This study aims at evaluating serum immunoglobulins A and E levels in patients suffering from Allergic in comparison with healthy individuals. Methods: This work was applied on 87 Allergiec patients admitted to the Babylon Center of Allergic and 40 apparently health controls with age range (10-69 years). . Results:The Immunological parameters showing that there is a significantly increased (p< 0.05) in IgE(448.75) IU/ml compared to control group (52.11) in age group10-19 and a significantly increased (p< 0.05) in IgA(380.5) mg/ml compared to control group (110.54 ) in age group 50-59 and no significantly increased (p> 0.05) of E-rosette test level in the allergic patients (32.601%) compared to control group (17.224%) in age group 50-59 years .Conclusion: We conclude that there is an association of all Allergic IgE level increase it in differant age also IgA level in serum of Allergic