Study the biochemical effects of Zinc sulphate on Dexamethasone treated male Iraqi sheep

Abstract

The experiments of present on twenty male Iraqi sheep were used in this study, (aged 2-4 years and weighted 40 ± 2 kg). Rams were divided equally and randomize into four main group (n = 5 each group). Group One: control group don’t treatment. Group Two: In this group the males injected dexamethasone 2 mg per animal intramuscularly injection for 4 weeks. Group Three: of this group were given zinc sulfate orally at a dose of 25 mg per animal per day. Group four: the males injected dexamethasone 2 mg per animal and given zinc sulfate orally at a dose of 25 mg per animal per day. This study was design to study the changes that occur in the some biochemical parameters related with the metabolism during hydrocortisone treatment and an attempt to overcome or at least inhibit the side effects of hydrocortisone by using zinc. From results of the present study it is concluded that dexamethasone treatment caused adverse effects elevating levels of serum glucose, lipids with no effect on total proteins and albumin, so should be cautious when there is a necessity to use dexamethasone especially but not long time.