Antifungal Activity Evalution of Punica granatum L. Extract against Candida albicans

Abstract

In the current study , it was highlighted to find out the inhibitory effect of the alcoholic extract of pomegranate peels against Candida albicans isolated from mouth area and around teeth through the period from the first of October of 2015 until the first of June of 2016. Different concentration of alcoholic extract of pomegranate peels were tested on the Yeast C.albicans by well diffusion method and microdilution method . The results showed that concentration( 150 , 100 , 50 , 25 , 12.5 ) mg/ ml of the crude extract gave inhibition zone diameter rates( 22 , 19.33 , 15.5 , 13.97 , 9 ) respectively, and the minimum inhibitory concentration ( MIC ) was ( 12.5 ) mg/ml against the yeast cells. From the current study , we concluded that, the high efficiency of alcoholic extract of Pomegranate against the yeast C.albicans, suggesting the possibility of its use as a treatment for patients with Candidiasis